Point-of-care (POC) or bedside diagnostics are becoming the ultimate need for improving medical treatment and better healthcare. The advantages of this strategy are rapid diagnosis, affordable cost, requirement of less expertise and possibility of being performed in resource limited healthcare settings. The development of POC diagnostics requires an inter-disciplinary approach which can improve diagnostic parameters like sensitivity and specificity and also enhance analysis with low sample volume. Advancements in microfluidic technology has enabled the researchers to develop such diagnostics, integrated with sensors for rapid and easy detection.
2. Kamat V, Pandey S, Paknikar K, Bodas D. A facile one-step method for cell lysis and DNA extraction of waterborne pathogens using a microchip. Biosens Bioelectron. 2018;99:62-9.
3. Bhagwat S, Sontakke S, K D, Parte P, Jadhav S. Chemotactic behavior of spermatozoa captured using a microfluidic chip. Biomicrofluidics. 2018;12(2):024112.
4. Bissoyi A, Bit A, Singh BK, Singh AK, Patra PK. Enhanced cryopreservation of MSCs in microfluidic bioreactor by regulated shear flow. Sci Rep. 2016;6:35416.
5. Zhou Y. The recent development and applications of fluidic channels by 3D printing. J Biomed Sci. 2017;24:80.
6. Chowdhury J, Kagiala GV, Pushpakom S, Lauzon J, Makin A, Atrazhev A, et al. Microfluidic platform for single nucleotide polymorphism genotyping of the thiopurine S-methyltransferase gene to evaluate risk for adverse drug events. J Mol Diagn. 2007;9:521-9.
7. Wang H, Zhang X, Xu X, Zhang Q, Wang H, Li D, et al. A portable microfluidic platform for rapid molecular diagnostic testing of patients with myeloproliferative neoplasms. Sci Rep. 2017;7:8596.